Enhanced IDOL segmentation framework using personalized hyperspace learning IDOL.

Journal: Medical physics
Published Date:

Abstract

BACKGROUND: Adaptive radiotherapy (ART) workflows have been increasingly adopted to achieve dose escalation and tissue sparing under shifting anatomic conditions, but the necessity of recontouring and the associated time burden hinders a real-time or online ART workflow. In response to this challenge, approaches to auto-segmentation involving deformable image registration, atlas-based segmentation, and deep learning-based segmentation (DLS) have been developed. Despite the particular promise shown by DLS methods, implementing these approaches in a clinical setting remains a challenge, namely due to the difficulty of curating a data set of sufficient size and quality so as to achieve generalizability in a trained model.

Authors

  • Byong Su Choi
    Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
  • Chris J Beltran
    Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
  • Sven Olberg
    Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, 63110, USA.
  • Xiaoying Liang
    2 University of Florida Proton Therapy Institute, Jacksonville, FL, USA.
  • Bo Lu
    Department of Radiation Oncology, University of Florida, Gainesville, FL, USA.
  • Jun Tan
    School of Mathematics, Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Alessio Parisi
    Department of Radiation Oncology, Mayo Clinic, Florida, USA.
  • Janet Denbeigh
    Department of Radiation Oncology, Mayo Clinic, Florida, USA.
  • Sridhar Yaddanapudi
    Department of Radiation Oncology, Mayo Clinic, Florida, USA.
  • Jin Sung Kim
    Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea.
  • Keith M Furutani
    Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, USA.
  • Justin C Park
    Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, 63110, USA.
  • Bongyong Song
    Department of Radiation Oncology, University of California San Diego, San Diego, California, USA.