AIMC Topic: Humans

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Identifying key brain pathology in bipolar and unipolar depression using a region-specific brain aging trajectories approach: Insights from the Taiwan Aging and Mental Illness Cohort.

Psychological medicine Aug 29, 2025
BACKGROUND: Identifying key areas of brain dysfunction in mental illness is critical for developing precision diagnosis and treatment. This study aimed to develop region-specific brain aging trajectory prediction models using multimodal magnetic reso...
Gray Matter Aged White Matter Bipolar Disorder Adult Diffusion Tensor Imaging Cohort Studies Male Taiwan Magnetic Resonance Imaging Humans Neuroimaging Brain Female Aging Middle Aged Depressive Disorder, Major
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A cross-sectional and bioinformatics-based analysis: perirenal fat thickness as a superior predictor of kidney stone disease.

Lipids in health and disease Aug 29, 2025
BACKGROUND: Kidney stone disease (KSD) is a growing global health concern, with obesity (OB) as a major risk factor linked to metabolic dysfunction and chronic inflammation. Although the common method for evaluating OB is body mass index (BMI), it is...
Kidney Body Mass Index Obesity Male Middle Aged Computational Biology Kidney Calculi Intra-Abdominal Fat Humans Retrospective Studies Tomography, X-Ray Computed Female Adult Cross-Sectional Studies
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Prediction-powered inference for clinical trials: application to linear covariate adjustment.

BMC medical research methodology Aug 29, 2025
Prediction-powered inference (PPI) (Angelopoulos et al., Science 382(6671):669-674, 2023) and its subsequent development called PPI++ (Angelopoulos et al., 2023) provide a novel approach to standard statistical estimation, leveraging machine learning...
Machine Learning Algorithms Prognosis Humans Sample Size Disease Progression Alzheimer Disease Linear Models Models, Statistical Randomized Controlled Trials as Topic
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Review of GPU-based Monte Carlo simulation platforms for transmission and emission tomography in medicine.

Physics in medicine and biology Aug 29, 2025
. Monte Carlo (MC) simulation remains the gold standard for modeling complex physical interactions in transmission and emission tomography, with graphic processing unit (GPU) parallel computing offering unmatched computational performance and enablin...
Humans Monte Carlo Method Medicine Computer Graphics Image Processing, Computer-Assisted Tomography
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Recent progress and perspective of magnetic miniature soft robot with multimodal locomotion.

Bioinspiration & biomimetics Aug 29, 2025
Multimodal miniature soft robots, with their higher movement flexibility and environmental adaptability, represent a crucial direction for the future development of soft robots. Magnetic-driven robots, owing to their advantages such as excellent remo...
Humans Animals Miniaturization Magnetics Robotics Locomotion Equipment Design Biomimetics
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SamRobNODDI:-space sampling-augmented continuous representation learning for robust and generalized NODDI.

Physics in medicine and biology Aug 29, 2025
. Neurite orientation dispersion and density imaging (NODDI) microstructure estimation from diffusion magnetic resonance imaging (dMRI) is of great significance for the discovery and treatment of various neurological diseases. Current deep learning-b...
Image Processing, Computer-Assisted Humans Neurites Machine Learning Diffusion Magnetic Resonance Imaging
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Integrated single-cell and clinical transcriptomic analysis identifies blunted glycolytic activation as a hallmark of maladaptive repair in renal ischemia-reperfusion.

Renal failure Aug 28, 2025
Acute kidney injury (AKI) is a common and increases risk of chronic kidney disease (CKD). While mitochondrial dysfunction drives maladaptive repair, the role of glycolysis in renal recovery remains unclear. Here, we integrated single-cell transcripto...
Renal Insufficiency, Chronic Disease Models, Animal Reperfusion Injury Glycolysis Kidney Animals Male Gene Expression Profiling Transcriptome Single-Cell Analysis Mice Kidney Transplantation Acute Kidney Injury Female Humans Machine Learning
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Parallel trade-offs in human cognition and neural networks: The dynamic interplay between in-context and in-weight learning.

Proceedings of the National Academy of Sciences of the United States of America Aug 28, 2025
Human learning embodies a striking duality: Sometimes, we can rapidly infer and compose logical rules, benefiting from structured curricula (e.g., in formal education), while other times, we rely on an incremental approach or trial-and-error, learnin...
Humans Cognition Neural Networks, Computer Memory, Short-Term Learning Nerve Net
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Echoes in AI: Quantifying lack of plot diversity in LLM outputs.

Proceedings of the National Academy of Sciences of the United States of America Aug 28, 2025
With rapid advances in large language models (LLMs), there has been an increasing application of LLMs in creative content ideation and generation. A critical question emerges: can current LLMs provide ideas that are diverse enough to truly bolster co...
Creativity Humans Artificial Intelligence Language
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Evaluating ChatGPT's Utility in Biologic Therapy for Systemic Lupus Erythematosus: Comparative Study of ChatGPT and Google Web Search.

JMIR formative research Aug 28, 2025
BACKGROUND: Systemic lupus erythematosus (SLE) is a life-threatening, multisystem autoimmune disease. Biologic therapy is a promising treatment for SLE. However, public understanding of this therapy is still insufficient, and the quality of related i...
Humans Artificial Intelligence Generative Artificial Intelligence Lupus Erythematosus, Systemic Internet Biological Therapy Search Engine
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