Tree-based ensemble machine learning models in the prediction of acute respiratory distress syndrome following cardiac surgery: a multicenter cohort study.

Journal: Journal of translational medicine
Published Date: Aug 15, 2024

Abstract

BACKGROUND: Acute respiratory distress syndrome (ARDS) after cardiac surgery is a severe respiratory complication with high mortality and morbidity. Traditional clinical approaches may lead to under recognition of this heterogeneous syndrome, potentially resulting in diagnosis delay. This study aims to develop and external validate seven machine learning (ML) models, trained on electronic health records data, for predicting ARDS after cardiac surgery.

Authors

  • Hang Zhang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Dewei Qian
    Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 85 Wujin Road, Shanghai, 200080, China.
  • Xiaomiao Zhang
    Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xinsongjiang Road, Shanghai, 201620, China.
  • Peize Meng
    Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xinsongjiang Road, Shanghai, 201620, China.
  • Weiran Huang
    Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China.
  • Tongtong Gu
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600 Yishan Road, Shanghai, 200233, China.
  • Yongliang Fan
    Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 85 Wujin Road, Shanghai, 200080, China.
  • Yi Zhang
    Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin University, Changchun, China.
  • Yuchen Wang
    College of Management, University of Massachusetts Boston, Boston, MA, USA.
  • Min Yu
    From the Division of Laboratory Medicine, Department of Pathology, University of Virginia School of Medicine and Health System, Charlottesville. Dr Yu is currently located in the Department of Pathology and Laboratory Medicine, University of Kentucky Medical Center, Lexington.
  • Zhongxiang Yuan
    Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 85 Wujin Road, Shanghai, 200080, China.
  • Xin Chen
    University of Nottingham, Nottingham, United Kingdom.
  • Qingnan Zhao
    Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xinsongjiang Road, Shanghai, 201620, China. zhaoqingnan2010@126.com.
  • Zheng Ruan
    Department of Geriatric Cardiology, General Hospital of the Southern Theatre Command, PLA, Guangzhou 510016, China.

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