AIMC Topic: Aged
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Development and validation of a risk prediction model for depression in patients with chronic obstructive pulmonary disease.
BMC psychiatry
Jul 3, 2025
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a prevalent respiratory condition often accompanied by depression, which exacerbates disease burden and impairs quality of life. Early identification of depression risk in COPD patients rema...
Integrating CT radiomics and clinical features using machine learning to predict post-COVID pulmonary fibrosis.
Respiratory research
Jul 2, 2025
BACKGROUND: The lack of reliable biomarkers for the early detection and risk stratification of post-COVID-19 pulmonary fibrosis (PCPF) underscores the urgency advanced predictive tools. This study aimed to develop a machine learning-based predictive ...
Exploring the complex associations between community public spaces and healthy aging: an explainable analysis using catboost and SHAP.
BMC public health
Jul 2, 2025
BACKGROUND: As global aging accelerates, community public spaces (CPS) are increasingly recognized as vital for promoting healthy aging. However, existing research often employs linear analytical methods or focuses on single health dimensions, overlo...
Machine learning-based integration identifies plasma cells-related gene signature ST6GAL1 in idiopathic pulmonary fibrosis.
BMC pulmonary medicine
Jul 2, 2025
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a rare, progressive, and fibrotic disease with poor prognosis that lacks treatment options. As a major component of the lung adaptive immune system, plasma cells play a crucial regulatory role during...
Enhanced machine learning models for predicting three-year mortality in Non-STEMI patients aged 75 and above.
BMC geriatrics
Jul 2, 2025
BACKGROUND: Non-ST segment elevation myocardial infarction (Non-STEMI) is a severe cardiovascular condition mainly affecting individuals aged 75 and above, who are at higher risk of mortality due to age-related vulnerabilities and other health issues...
Interpretable machine learning for depression recognition with spatiotemporal gait features among older adults: a cross-sectional study in Xiamen, China.
BMC geriatrics
Jul 2, 2025
OBJECTIVE: Depression in older adults is a growing public health concern, yet there is still a lack of convenient and real-time methods for depressive symptoms identification. This study aims to develop a gait-based depression recognition method for ...
A deep learning model for early diagnosis of alzheimer's disease combined with 3D CNN and video Swin transformer.
Scientific reports
Jul 2, 2025
Alzheimer's disease (AD) constitutes a neurodegenerative disorder predominantly observed in the geriatric population. If AD can be diagnosed early, both in terms of prevention and treatment, it is very beneficial to patients. Therefore, our team prop...
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis.
Nature communications
Jul 2, 2025
Approximately 40% of patients with rheumatoid arthritis do not respond to individual biologic therapies, while biomarkers predictive of treatment response are lacking. Here we analyse RNA-sequencing (RNA-Seq) of pre-treatment synovial tissue from the...
Design of a Mobile App and a Clinical Trial Management System for Cognitive Health and Dementia Risk Reduction: User-Centered Design Approach.
JMIR aging
Jul 2, 2025
BACKGROUND: The rising prevalence of dementia is a major concern, with approximately 45% of cases linked to 14 modifiable risk factors. The European project LETHE aims to develop a personalized digital intervention model to delay or prevent cognitive...
A deep learning-based computed tomography reading system for the diagnosis of lung cancer associated with cystic airspaces.
Scientific reports
Jul 2, 2025
To propose a deep learning model and explore its performance in the auxiliary diagnosis of lung cancer associated with cystic airspaces (LCCA) in computed tomography (CT) images. This study is a retrospective analysis that incorporated a total of 342...
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