AIMC Topic: Middle Aged

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Deep learning model for predicting extraprostatic extension of prostate cancer based on H&E-stained biopsy digital images.

Annals of medicine
BACKGROUND: To develop and validate a deep learning pipeline using prostate biopsy H&E slides to predict extraprostatic extension (EPE) in prostate cancer (PCa) patients.

Artificial intelligence model for predicting early biochemical recurrence of prostate cancer after robotic-assisted radical prostatectomy.

Scientific reports
Prostate cancer remains a significant public health concern, with a substantial proportion of patients experiencing biochemical recurrence (BCR) after radical prostatectomy (RP). Traditional risk models, such as CAPRA-S, have demonstrated moderate pr...

CT-based machine learning model integrating intra- and peri-tumoral radiomics features for predicting occult lymph node metastasis in peripheral lung cancer.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Accurate preoperative assessment of occult lymph node metastasis (OLNM) plays a crucial role in informing therapeutic decision-making for lung cancer patients. Computed tomography (CT) is the most widely used imaging modality for preopera...

Artificial intelligence-based prediction of treatment failure and medication non-adherence in overactive bladder management.

BMC urology
BACKGROUND: Overactive bladder management presents significant challenges, with treatment failures and medication non-adherence posing substantial barriers to patient outcomes. Early prediction of these challenges could enable timely interventions an...

Racial and socioeconomic disparities in long term survival after surgery and radiation for spinal cord hemangioblastoma.

Scientific reports
Spinal cord hemangioblastomas are rare, benign, intradural tumors that, despite their nonmalignant histopathology, can lead to substantial neurological morbidity. While disparities in outcomes based on race and socioeconomic status have been well-doc...

Supervised machine learning algorithms for the classification of obesity levels using anthropometric indices derived from bioelectrical impedance analysis.

Scientific reports
The accurate classification of obesity is essential for public health and clinical decision-making. Traditional anthropometric measures such as body mass index (BMI) have limitations in differentiating between fat and lean mass. This study aimed to e...

Discovery of tumour indicating morphological changes in benign prostate biopsies through AI.

Scientific reports
Diagnostic needle biopsies that miss clinically significant prostate cancer (PCa) often sample benign tissue near hidden cancers. Such benign samples might still display subtle morphological signs of cancer elsewhere in the prostate. This study exami...

Natural language processing assisted detection of inappropriate proton pump inhibitor use in adult hospitalised patients.

European journal of hospital pharmacy : science and practice
OBJECTIVES: To establish a clinical application monitoring system for proton pump inhibitors (PPI-MS) and to enhance the detection and intervention of inappropriate PPI use in adult hospitalised patients.

Predicting knee osteoarthritis progression using neural network with longitudinal MRI radiomics, and biochemical biomarkers: A modeling study.

PLoS medicine
BACKGROUND: Knee osteoarthritis (KOA) worsens both structurally and symptomatically, yet no model predicts KOA progression using Magnetic Resonance Image (MRI) radiomics and biomarkers. This study aimed to develop and test the longitudinal Load-Beari...

The additive effect of the estimated glucose disposal rate and a body shape index on cardiovascular disease: A cross-sectional study.

PloS one
BACKGROUND: The glucose disposal rate (eGDR) and a body shape index (ABSI) are predictors strongly associated with cardiovascular disease (CVD) and outcomes. However, whether they have additive effects on CVD risk is unknown. This study aimed to inve...