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Identifying key brain pathology in bipolar and unipolar depression using a region-specific brain aging trajectories approach: Insights from the Taiwan Aging and Mental Illness Cohort.
Psychological medicine
Aug 29, 2025
BACKGROUND: Identifying key areas of brain dysfunction in mental illness is critical for developing precision diagnosis and treatment. This study aimed to develop region-specific brain aging trajectory prediction models using multimodal magnetic reso...
A cross-sectional and bioinformatics-based analysis: perirenal fat thickness as a superior predictor of kidney stone disease.
Lipids in health and disease
Aug 29, 2025
BACKGROUND: Kidney stone disease (KSD) is a growing global health concern, with obesity (OB) as a major risk factor linked to metabolic dysfunction and chronic inflammation. Although the common method for evaluating OB is body mass index (BMI), it is...
Integrated single-cell and clinical transcriptomic analysis identifies blunted glycolytic activation as a hallmark of maladaptive repair in renal ischemia-reperfusion.
Renal failure
Aug 28, 2025
Acute kidney injury (AKI) is a common and increases risk of chronic kidney disease (CKD). While mitochondrial dysfunction drives maladaptive repair, the role of glycolysis in renal recovery remains unclear. Here, we integrated single-cell transcripto...
Nasopharyngeal cancer adaptive radiotherapy with CBCT-derived synthetic CT: deep learning-based auto-segmentation precision and dose calculation consistency on a C-Arm linac.
Radiation oncology (London, England)
Aug 28, 2025
BACKGROUND: To evaluate the precision of automated segmentation facilitated by deep learning (DL) and dose calculation in adaptive radiotherapy (ART) for nasopharyngeal cancer (NPC), leveraging synthetic CT (sCT) images derived from cone-beam CT (CBC...
Machine learning in predicting preoperative intra-aortic balloon pump use in patients undergoing coronary artery bypass grafting.
Journal of cardiothoracic surgery
Aug 28, 2025
BACKGROUND: Intra-aortic balloon pump (IABP) implantation in the perioperative period of cardiac surgery is an auxiliary treatment for cardiogenic shock. However, there is a lack of effective prediction models for preoperative IABP implantation.
Predicting survival factor following suicide attempt in Iran: an ensemble machine learning technique.
BMC psychiatry
Aug 28, 2025
BACKGROUND: Suicide represents a significant challenge to public health that calls for a suitable intervention from the healthcare sector. Despite the typically low suicide rate among most Muslim nations, research indicates that there is an increase ...
Health-economic evaluation of an AI-powered decision support system for anemia management in in-center hemodialysis patients.
BMC nephrology
Aug 28, 2025
BACKGROUND: The Anemia Control Model (ACM) is a decision support system powered by an artificial intelligence core designed to assist nephrologists in managing anemia therapy for in-center hemodialysis (HD) patients. This study aims to evaluate the c...
AI-Driven Tai Chi mastery using deep learning framework for movement assessment and personalized training.
Scientific reports
Aug 28, 2025
This paper presents a novel system for optimizing Tai Chi movement training using computer vision and deep learning technologies. We developed a comprehensive framework incorporating multi-view pose estimation, temporal feature extraction, and real-t...
Testing an adapted obesity prevention intervention in under resourced schools: a pilot clustered randomized controlled trial.
Scientific reports
Aug 28, 2025
The purpose of this pilot study was to test an adapted childhood obesity prevention intervention called Preventing Obesity Using Digital-Assisted Movement and Eating (ProudMe) in under-resourced schools. Six schools were cluster-randomized to ProudMe...
Immune metabolic changes identify causal candidate genes and enable diagnostic frameworks in MAFLD.
Scientific reports
Aug 28, 2025
Metabolic dysfunction-associated fatty liver disease (MAFLD), a global epidemic affecting 25% of adults, is driven by immune-metabolic dysregulation, yet the causal mechanisms linking immune cell-specific gene perturbations to disease progression rem...
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