Leveraging foundation and large language models in medical artificial intelligence.

Journal: Chinese medical journal
Published Date:

Abstract

Recent advancements in the field of medical artificial intelligence (AI) have led to the widespread adoption of foundational and large language models. This review paper explores their applications within medical AI, introducing a novel classification framework that categorizes them as disease-specific, general-domain, and multi-modal models. The paper also addresses key challenges such as data acquisition and augmentation, including issues related to data volume, annotation, multi-modal fusion, and privacy concerns. Additionally, it discusses the evaluation, validation, limitations, and regulation of medical AI models, emphasizing their transformative potential in healthcare. The importance of continuous improvement, data security, standardized evaluations, and collaborative approaches is highlighted to ensure the responsible and effective integration of AI into clinical applications.

Authors

  • Io Nam Wong
    Institute for AI in Medicine, Faculty of Medicine, Macau University of Science and Technology, Macau Special Administrative Region 999078, China.
  • Olivia Monteiro
    Center for Biomedicine and Innovations, Faculty of Medicine, Macau University of Science and Technology, Macao 999078, China.
  • Daniel T Baptista-Hon
    Instutite for Artificial Intelligence in Medicine and Faculty of Medicine, Macau University of Science and Technology, Macau, China.
  • Kai Wang
    Department of Rheumatology, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
  • Wenyang Lu
    Institute for Advanced Study on Eye Health and Diseases, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Zhuo Sun
    State Key Laboratory of Eye Health, Eye Hospital and Institute for Advanced Study on Eye Health and Diseases, Wenzhou Medical University, Wenzhou, China; Department of Ophthalmology, The Third People's Hospital of Changzhou, Changzhou, China.
  • Sheng Nie
    State Key Laboratory of Organ Failure Research, National Clinical Research Center for Kidney Disease and Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Yun Yin
    Faculty of Health and Wellness, Faculty of Business, City University of Macau, Macau, China.