Deep learning model for automated diagnosis of degenerative cervical spondylosis and altered spinal cord signal on MRI.

Journal: The spine journal : official journal of the North American Spine Society
PMID:

Abstract

BACKGROUND CONTEXT: A deep learning (DL) model for degenerative cervical spondylosis on MRI could enhance reporting consistency and efficiency, addressing a significant global health issue.

Authors

  • Aric Lee
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore.
  • Junran Wu
    Department of Computer Science, School of Computing, National University of Singapore, 13 Computing Drive 117417, Singapore.
  • Changshuo Liu
    Department of Computer Science, School of Computing, National University of Singapore, 13 Computing Drive 117417, Singapore.
  • Andrew Makmur
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); NUS Graduate School, Integrative Sciences and Engineering Programme, National University of Singapore, Singapore (L.Z.); Department of Computer Science, School of Computing, National University of Singapore, Singapore (K.Y., B.C.O.); Department of Radiology, Dammam Medical Complex, Dammam, Saudi Arabia (D.A.R.A.); Biostatistics Unit, Yong Loo Lin School of Medicine, Singapore (Q.V.Y., Y.H.C.); University Spine Centre, Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • Yong Han Ting
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore; Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Faimee Erwan Muhamat Nor
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore; Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Loon Ying Tan
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore; Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Wilson Ong
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore.
  • Wei Chuan Tan
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (D.S.W.L., A.M., A.J.L.C., D.S.Y.S., S.E.E., H.Y.O., P.J., W.C.T., V.M.K., Y.M.W., Y.L.T., S.B., E.C.T., S.T.Q., J.T.P.D.H.); Department of Diagnostic Radiology (A.M., S.E.E., P.J., Y.L.T., S.T.Q., J.T.P.D.H.), NUS Graduate School, Integrative Sciences and Engineering Programme (L.Z.), Department of Computer Science, School of Computing (W.Z., B.C.O.), and Biostatistics Unit, Yong Loo Lin School of Medicine (Q.V.Y., Y.H.C.), National University of Singapore, Singapore; Department of Radiology, Qatif Central Hospital, Qatif, Saudi Arabia (D.A.R.A.); Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • You Jun Lee
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore.
  • Juncheng Huang
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd 119074, Singapore.
  • Joey Chan Yiing Beh
    Department of Radiology, Ng Teng Fong General Hospital, 1 Jurong East Street 21 609606, Singapore.
  • Desmond Shi Wei Lim
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (D.S.W.L., A.M., A.J.L.C., D.S.Y.S., S.E.E., H.Y.O., P.J., W.C.T., V.M.K., Y.M.W., Y.L.T., S.B., E.C.T., S.T.Q., J.T.P.D.H.); Department of Diagnostic Radiology (A.M., S.E.E., P.J., Y.L.T., S.T.Q., J.T.P.D.H.), NUS Graduate School, Integrative Sciences and Engineering Programme (L.Z.), Department of Computer Science, School of Computing (W.Z., B.C.O.), and Biostatistics Unit, Yong Loo Lin School of Medicine (Q.V.Y., Y.H.C.), National University of Singapore, Singapore; Department of Radiology, Qatif Central Hospital, Qatif, Saudi Arabia (D.A.R.A.); Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • Xi Zhen Low
    Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
  • Ee Chin Teo
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (D.S.W.L., A.M., A.J.L.C., D.S.Y.S., S.E.E., H.Y.O., P.J., W.C.T., V.M.K., Y.M.W., Y.L.T., S.B., E.C.T., S.T.Q., J.T.P.D.H.); Department of Diagnostic Radiology (A.M., S.E.E., P.J., Y.L.T., S.T.Q., J.T.P.D.H.), NUS Graduate School, Integrative Sciences and Engineering Programme (L.Z.), Department of Computer Science, School of Computing (W.Z., B.C.O.), and Biostatistics Unit, Yong Loo Lin School of Medicine (Q.V.Y., Y.H.C.), National University of Singapore, Singapore; Department of Radiology, Qatif Central Hospital, Qatif, Saudi Arabia (D.A.R.A.); Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • Yiong Huak Chan
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); NUS Graduate School, Integrative Sciences and Engineering Programme, National University of Singapore, Singapore (L.Z.); Department of Computer Science, School of Computing, National University of Singapore, Singapore (K.Y., B.C.O.); Department of Radiology, Dammam Medical Complex, Dammam, Saudi Arabia (D.A.R.A.); Biostatistics Unit, Yong Loo Lin School of Medicine, Singapore (Q.V.Y., Y.H.C.); University Spine Centre, Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • Joshua Ian Lim
    Division of Spine Surgery, Department of Orthopaedic Surgery, Ng Teng Fong General Hospital, 1 Jurong East Street 21 609606, Singapore.
  • Shuxun Lin
    Division of Spine Surgery, Department of Orthopaedic Surgery, Ng Teng Fong General Hospital, 1 Jurong East Street 21 609606, Singapore.
  • Jiong Hao Tan
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); NUS Graduate School, Integrative Sciences and Engineering Programme, National University of Singapore, Singapore (L.Z.); Department of Computer Science, School of Computing, National University of Singapore, Singapore (K.Y., B.C.O.); Department of Radiology, Dammam Medical Complex, Dammam, Saudi Arabia (D.A.R.A.); Biostatistics Unit, Yong Loo Lin School of Medicine, Singapore (Q.V.Y., Y.H.C.); University Spine Centre, Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • Naresh Kumar
    Department of Computer Science & Engineering, Maharaja Surajmal Institute of Technology, C-4, Janakpuri, New Delhi 110058, India.
  • Beng Chin Ooi
    School of Computing, National University of Singapore, Singapore, Singapore.
  • Swee Tian Quek
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); NUS Graduate School, Integrative Sciences and Engineering Programme, National University of Singapore, Singapore (L.Z.); Department of Computer Science, School of Computing, National University of Singapore, Singapore (K.Y., B.C.O.); Department of Radiology, Dammam Medical Complex, Dammam, Saudi Arabia (D.A.R.A.); Biostatistics Unit, Yong Loo Lin School of Medicine, Singapore (Q.V.Y., Y.H.C.); University Spine Centre, Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).
  • James Thomas Patrick Decourcy Hallinan
    From the Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074 (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore (J.T.P.D.H., A.M., Y.L.T., S.L., Y.S.C., S.E.E., S.T.Q.); NUS Graduate School, Integrative Sciences and Engineering Programme, National University of Singapore, Singapore (L.Z.); Department of Computer Science, School of Computing, National University of Singapore, Singapore (K.Y., B.C.O.); Department of Radiology, Dammam Medical Complex, Dammam, Saudi Arabia (D.A.R.A.); Biostatistics Unit, Yong Loo Lin School of Medicine, Singapore (Q.V.Y., Y.H.C.); University Spine Centre, Department of Orthopaedic Surgery, National University Health System, Singapore (J.H.T., N.K.); and Department of Radiological Sciences, University of California, Irvine, Orange, Calif (H.Y.).