SCINet: A Segmentation and Classification Interaction CNN Method for Arteriosclerotic Retinopathy Grading.

Journal: Interdisciplinary sciences, computational life sciences
PMID:

Abstract

As a common disease, cardiovascular and cerebrovascular diseases pose a great harm threat to human wellness. Even using advanced and comprehensive treatment methods, there is still a high mortality rate. Arteriosclerosis, as an important factor reflecting the severity of cardiovascular and cerebrovascular diseases, is imperative to detect the arteriosclerotic retinopathy. However, the detection of arteriosclerosis retinopathy requires expensive and time-consuming manual evaluation, while end-to-end deep learning detection methods also need interpretable design to high light task-related features. Considering the importance of automatic arteriosclerotic retinopathy grading, we propose a segmentation and classification interaction network (SCINet). We propose a segmentation and classification interaction architecture for grading arteriosclerotic retinopathy. After IterNet is used to segment retinal vessel from original fundus images, the backbone feature extractor roughly extracts features from the segmented and original fundus arteriosclerosis images and further enhances them through the vessel aware module. The last classifier module generates fundus arteriosclerosis grading results. Specifically, the vessel aware module is designed to highlight the important areal vessel features segmented from original images by attention mechanism, thereby achieving information interaction. The attention mechanism selectively learns the vessel features of segmentation region information under the proposed interactive architecture, which leads to reweighting the extracted features and enhances significant feature information. Extensive experiments have confirmed the effect of our model. SCINet has the best performance on the task of arteriosclerotic retinopathy grading. Additionally, the CNN method is scalable to similar tasks by incorporating segmented images as auxiliary information.

Authors

  • Xiongwen Quan
    College of Artificial Intelligence, Nankai University, Tongyan Road, Tianjin, 300350, China.
  • Xingyuan Ou
    College of Artificial Intelligence, Nankai University, Tianjin, China.
  • Li Gao
    College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, China.
  • Wenya Yin
    National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Engineering Research Center of Trusted Behavior Intelligence, Ministry of Education, College of Artificial Intelligence, Nankai University, Tianjin, 300000, China.
  • Guangyao Hou
    National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Engineering Research Center of Trusted Behavior Intelligence, Ministry of Education, College of Artificial Intelligence, Nankai University, Tianjin, 300000, China.
  • Han Zhang
    Johns Hopkins University, Baltimore, MD, USA.