FertilitY Predictor-a machine learning-based web tool for the prediction of assisted reproduction outcomes in men with Y chromosome microdeletions.

Journal: Journal of assisted reproduction and genetics
PMID: 39652237

Abstract

PURPOSE: Y chromosome microdeletions (YCMD) are a common cause of azoospermia and oligozoospermia in men. Herein, we developed a machine learning-based web tool to predict sperm retrieval rates and success rates of assisted reproduction (ART) in men with YCMD.

Authors

  • Stacy Colaco
    Molecular and Cellular Biology Laboratory, ICMR-National Institute for Research in Reproductive and Child Health, JM Street, Parel, Mumbai, Maharashtra, 400012, India.
  • Priyanka Narad
    Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India. Electronic address: pnarad@amity.edu.
  • Ajit Kumar Singh
    Systems Biology and Data Analytics Research Laboratory Centre for Computational Biology and Bioinformatics, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.
  • Payal Gupta
    Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
  • Alakto Choudhury
    Centre for Computational Biology and Bioinformatics, AIB, Amity University, Noida, Uttar Pradesh, India.
  • Abhishek Sengupta
    Amity Institute of Biotechnology, Amity University Uttar Pradesh, U.P., India.
  • Deepak Modi
    Molecular and Cellular Biology Laboratory, National Institute for Research in Reproductive and Child Health, Mumbai, Maharashtra, India.

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