A Comprehensive Review of Artificial Intelligence (AI) Applications in Pulmonary Hypertension (PH).

Journal: Medicina (Kaunas, Lithuania)
PMID:

Abstract

Pulmonary hypertension (PH) is a complex condition associated with significant morbidity and mortality. Traditional diagnostic and management approaches for PH often face limitations, leading to delays in diagnosis and potentially suboptimal treatment outcomes. Artificial intelligence (AI), encompassing machine learning (ML) and deep learning (DL) offers a transformative approach to PH care. We systematically searched PubMed, Scopus, and Web of Science for original studies on AI applications in PH, using predefined keywords. Out of more than 500 initial articles, 45 relevant studies were selected. Risk of bias was evaluated using PROBAST (Prediction model Risk of Bias Assessment Tool). This review examines the potential applications of AI in PH, focusing on its role in enhancing diagnosis, disease classification, and prognostication. We discuss how AI-powered analysis of medical data can improve the accuracy and efficiency of detecting PH. Furthermore, we explore the potential of AI in risk stratification, leading to treatment optimization for PH. While acknowledging the existing challenges and limitations and the need for continued exploration and refinement of AI-driven tools, this review highlights the significant promise of AI in revolutionizing PH management to improve patient outcomes.

Authors

  • Sogol Attaripour Esfahani
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Nima Baba Ali
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Juan M Farina
    Mayo Clinic Arizona, Scottsdale, Arizona, USA.
  • Isabel G Scalia
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Milagros Pereyra
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Mohammed Tiseer Abbas
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Niloofar Javadi
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Nadera N Bismee
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Fatmaelzahraa E Abdelfattah
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Kamal Awad
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Omar H Ibrahim
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Hesham Sheashaa
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Timothy Barry
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Robert L Scott
    Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
  • Chadi Ayoub
    Mayo Clinic Arizona, Scottsdale, Arizona, USA.
  • Reza Arsanjani
    Department of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ.