Mortality prediction after major surgery in a mixed population through machine learning: a multi-objective symbolic regression approach.

Journal: Anaesthesia
PMID: 39778909

Abstract

INTRODUCTION: Understanding 1-year mortality following major surgery offers valuable insights into patient outcomes and the quality of peri-operative care. Few models exist that predict 1-year mortality accurately. This study aimed to develop a predictive model for 1-year mortality in patients undergoing complex non-cardiac surgery using a novel machine-learning technique called multi-objective symbolic regression.

Authors

  • Pietro Arina
    Bloomsbury Institute of Intensive Care Medicine and Human Physiology and Performance Laboratory, Centre for Perioperative Medicine, Department of Targeted Intervention, University College London, London, United Kingdom.
  • Davide Ferrari
    Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Nicholas Tetlow
    Human Physiology and Performance Laboratory, Centre for Perioperative Medicine, Research Department of Targeted Intervention, University College London, London, UK.
  • Amy Dewar
    Human Physiology and Performance Laboratory, Centre for Perioperative Medicine, Research Department of Targeted Intervention, University College London, London, UK.
  • Robert Stephens
    Human Physiology and Performance Laboratory, Centre for Perioperative Medicine, Research Department of Targeted Intervention, University College London, London, UK.
  • Daniel Martin
    Department of Economics, University of California, Santa Barbara, Santa Barbara, California, United States of America.
  • Ramani Moonesinghe
    Human Physiology and Performance Laboratory, Centre for Perioperative Medicine, Research Department of Targeted Intervention, University College London, London, UK.
  • Vasa Curcin
    Department of Population Health Sciences King's College London London UK.
  • Mervyn Singer
    Bloomsbury Institute of Intensive Care Medicine, University College London, London, United Kingdom.
  • John Whittle
    Human Physiology and Performance Laboratory, Centre for Perioperative Medicine, Department of Targeted Intervention, University College London, London, United Kingdom.
  • Evangelos B Mazomenos
    Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London W1W 7TY, UK.

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