From challenges and pitfalls to recommendations and opportunities: Implementing federated learning in healthcare.

Journal: Medical image analysis
PMID:

Abstract

Federated learning holds great potential for enabling large-scale healthcare research and collaboration across multiple centers while ensuring data privacy and security are not compromised. Although numerous recent studies suggest or utilize federated learning based methods in healthcare, it remains unclear which ones have potential clinical utility. This review paper considers and analyzes the most recent studies up to May 2024 that describe federated learning based methods in healthcare. After a thorough review, we find that the vast majority are not appropriate for clinical use due to their methodological flaws and/or underlying biases which include but are not limited to privacy concerns, generalization issues, and communication costs. As a result, the effectiveness of federated learning in healthcare is significantly compromised. To overcome these challenges, we provide recommendations and promising opportunities that might be implemented to resolve these problems and improve the quality of model development in federated learning with healthcare.

Authors

  • Ming Li
    Radiology Department, Huadong Hospital, Affiliated with Fudan University, Shanghai, China.
  • Pengcheng Xu
  • Junjie Hu
    Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, PR China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, PR China.
  • Zeyu Tang
  • Guang Yang
    National Heart and Lung Institute, Imperial College London, London, UK.