Leaf-Face Classifier Based on an Integrated Electrochemical Tongue and Machine Learning.

Journal: ACS sensors
PMID:

Abstract

Botanical sourcing seriously impacts the safety and potency of herbal medicines, restricting the development of the traditional Chinese medicinal industry. Rapid and convenient identification of plant resources is important to address this problem. Herein, we innovated a portable, intelligent, and integrated platform, termed the Smart Electronic Tongue (SET), for right recognizing bonsai of different subspecies and origins. The device is miniaturized with a hollow microneedle array for leaf-face extraction, a press-pumping pipeline for on-demand sample sap suction, plus a five-electrode chip for electrochemical readout. Differential pulse voltammograms on three simplexes of self-assembled monolayers as well as their multiplexed configurations are specialized to generate high-dimensional fingerprinting of subtypes. Taking advantage of machine learning algorithms, the platform achieves automatic authentication over eight varieties with a discriminatory accuracy of 95%. Given this, we anticipate that such a bionic sensing setup would offer a versatile solution toward the classification of diverse officinals at the point of need.

Authors

  • Yaqi Huang
    School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Yueyu Wang
    School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Fulin Zhu
    School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Yuxiao He
    School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Kelan Yan
    Key Laboratory of Metabolic Engineering and Biosynthesis Technology of Ministry of Industry and Information Technology, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Jie Chen
    School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, China.
  • Yuhao Piao
    Key Laboratory of Metabolic Engineering and Biosynthesis Technology of Ministry of Industry and Information Technology, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Yan Su
    State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences (ICMS), University of Macau, Macau, China.
  • Ying Wan
    Department of Mathematics, Southeast University, Nanjing 210096, China.
  • Tiantian Man
    School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.
  • Shengyuan Deng
    Key Laboratory of Metabolic Engineering and Biosynthesis Technology of Ministry of Industry and Information Technology, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China.