Artificial Intelligence Improves Prediction of Major Adverse Cardiovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement Planning CT.

Journal: Academic radiology
PMID:

Abstract

RATIONALE AND OBJECTIVES: Coronary CT angiography (CCTA) is mandatory before transcatheter aortic valve replacement (TAVR). Our objective was to evaluate the efficacy of artificial intelligence (AI)-powered software in automatically analyzing cardiac parameters from pre-procedural CCTA to predict major adverse cardiovascular events (MACE) in TAVR patients.

Authors

  • Giuseppe Tremamunno
    Radiology Unit, Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
  • Milán Vecsey-Nagy
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
  • U Joseph Schoepf
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29425-2260 (S.S.M., D.M., M.v.A., C.N.D.C., R.R.B., C.T., A.V.S., A.M.F., B.E.J., L.P.G., U.J.S.); Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany (S.S.M., T.J.V.); Stanford University School of Medicine, Department of Radiology, Stanford, Calif (D.M.); Division of Cardiothoracic Imaging, Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (C.N.D.C.); Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC (R.R.B.); Department of Cardiology and Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich, Germany (C.T.); Department of Cardiology, Munich University Clinic, Ludwig-Maximilians-University, Munich, Germany (C.T.); Siemens Medical Solutions USA, Malvern, Pa (P.S.); and Department of Emergency Medicine, Medical University of South Carolina, Charleston, SC (A.J.M.).
  • Emese Zsarnóczay
    Medical Imaging Centre, Semmelweis University, Budapest, Hungary.
  • Gilberto J Aquino
    Medical University of South Carolina, Department of Radiology and Radiological Science, USA.
  • Dmitrij Kravchenko
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
  • Andrea Laghi
    Department of Radiological Sciences, Oncology and Pathology, University La Sapienza, AOU Sant'Andrea, Via di Grottarossa 1035, 00189 Rome, Italy.
  • Athira Jacob
    Siemens Healthineers, Princeton, NJ, USA.
  • Puneet Sharma
    Digital Technologies and Innovation, Siemens Healthineers, Princeton, NJ, United States.
  • Saikiran Rapaka
    From the Division of Cardiovascular Imaging, Department of Radiology and Radiological Science (C.T., C.N.D.C., S.B., M.R., T.W.M., T.M.D., R.R.B., U.J.S.), and Division of Cardiology, Department of Medicine (R.R.B., D.H.S., U.J.S.), Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29425-2260; Department of Computed Tomography-Research & Development, Siemens Healthcare GmbH, Forchheim, Germany (K.L.G., C.C., C.S., M.S.); Department of Corporate Technology, Siemens SRL, Brasov, Romania (L.M.I.); and Department of Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (S.R., P.S.).
  • Jim O'Doherty
    Siemens Healthineers, Princeton, New Jersey.
  • Pal Spruill Suranyi
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, South Carolina 29425, USA (G.T., M.V.N., U.J.S., E.Z., G.J.A., D.K., J.O., P.S.S., I.M.K., T.E., A.V.S.).
  • Ismail Mikdat Kabakus
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, South Carolina 29425, USA (G.T., M.V.N., U.J.S., E.Z., G.J.A., D.K., J.O., P.S.S., I.M.K., T.E., A.V.S.).
  • Nicholas S Amoroso
    Division in Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA.
  • Daniel H Steinberg
    Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
  • Tilman Emrich
    Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA.
  • Akos Varga-Szemes
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29425-2260 (S.S.M., D.M., M.v.A., C.N.D.C., R.R.B., C.T., A.V.S., A.M.F., B.E.J., L.P.G., U.J.S.); Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany (S.S.M., T.J.V.); Stanford University School of Medicine, Department of Radiology, Stanford, Calif (D.M.); Division of Cardiothoracic Imaging, Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (C.N.D.C.); Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC (R.R.B.); Department of Cardiology and Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich, Germany (C.T.); Department of Cardiology, Munich University Clinic, Ludwig-Maximilians-University, Munich, Germany (C.T.); Siemens Medical Solutions USA, Malvern, Pa (P.S.); and Department of Emergency Medicine, Medical University of South Carolina, Charleston, SC (A.J.M.).