Transfer Learning Enhanced Blood Pressure Monitoring Based on Flexible Optical Pulse Sensing Patch.

Journal: ACS sensors
PMID:

Abstract

Blood pressure (BP), a crucial health biomarker, is essential for detecting early indications of cardiovascular disease in routine monitoring and clinical surveillance of inpatients. However, conventional cuff-based BP measurements are limited in providing continuous comfort monitoring. Here, we present an optical pulse sensing patch for BP monitoring, which integrates three units of Gallium Nitride (GaN) optopairs with micronanostructured polydimethylsiloxane films to capture pulse waves. Multipoint pulse signals are transformed into BP and other cardiovascular indicators through machine learning. The transfer learning method is developed to calibrate the machine learning model with few training sets, simplifying the practical implementation. The developed sensing patch holds great potential for long-term, precise BP monitoring, enhancing clinical diagnosis, and management of cardiovascular diseases.

Authors

  • Zecong Liu
    School of Microelectronics, Southern University of Science and Technology, Shenzhen 518055, P.R. China.
  • Chao Xiang
    State Key Laboratory of Chemo and Biosensing College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China.
  • Yeyu Tong
    Microelectronic Thrust, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou 511453, Guangdong, China.
  • Kwai Hei Li
    School of Microelectronics, Southern University of Science and Technology, Shenzhen 518055, P.R. China.
  • Xun Guan
    Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, Guangdong, China.