Leveraging deep learning for improving parameter extraction from perfusion MR images: A narrative review.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Published Date:

Abstract

BACKGROUND: Perfusion magnetic resonance imaging (MRI) is a non-invasive technique essential for assessing tissue microcirculation and perfusion dynamics. Various perfusion MRI techniques like Dynamic Contrast-Enhanced (DCE), Dynamic Susceptibility Contrast (DSC), Arterial Spin Labeling (ASL), and Intravoxel Incoherent Motion (IVIM) provide critical insights into physiological and pathological processes. However, traditional methods for quantifying perfusion parameters are time-consuming, often prone to variability, and limited by noise and complex tissue dynamics. Recent advancements in artificial intelligence (AI), particularly in deep learning (DL), offer potential solutions to these challenges. DL algorithms can process large datasets efficiently, providing faster, more accurate parameter extraction with reduced subjectivity.

Authors

  • Elisa Scalco
    National Research Council of Italy - Institute of Molecular Bioimaging and Physiology (IBFM), Via F.lli Cervi 93, 20090 Segrate, MI, Italy.
  • Giovanna Rizzo
    National Research Council of Italy - Institute of Molecular Bioimaging and Physiology (IBFM), Via F.lli Cervi 93, 20090 Segrate, MI, Italy.
  • Nicola Bertolino
    Department of Radiology, Northwestern University, Chicago, Illinois, USA.
  • Alfonso Mastropietro