AI-PEDURO - Artificial intelligence in pediatric urology: Protocol for a living scoping review and online repository.

Journal: Journal of pediatric urology
PMID:

Abstract

BACKGROUND: Artificial intelligence (AI) and machine learning (ML) methods are increasingly being applied in pediatric urology across a growing number of settings, with more extensive databases and wider interest for use in clinical practice. More than 30 ML models have been published in the pediatric urology literature, but many lack items required by contemporary reporting frameworks to be high quality. For example, most studies lack multi-institution validation, validation over time, and validation within the clinical environment, resulting in a large discrepancy between the number of models developed versus the number of models deployed in a clinical setting, a phenomenon known as the AI chasm. Furthermore, pediatric urology is a unique subspecialty of urology with low frequency conditions and complex phenotypes where clinical management can rely on a lower quality of evidence.

Authors

  • Adree Khondker
    Division of Urology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
  • Jethro C C Kwong
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Mandy Rickard
    Department of Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Lauren Erdman
    Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Andrew T Gabrielson
    The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • David-Dan Nguyen
    Faculty of Medicine, McGill University, Montreal, QC, Canada.
  • Jin Kyu Kim
    Department of Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada kimjink@iu.edu.
  • Tariq Abbas
    Division of Urology, Sidra Medicine, Doha, Qatar.
  • Nicolás Fernández
    Division of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., Colombia.
  • Katherine Fischer
    Department of Surgery, Division of Pediatric Urology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States; Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
  • Lisette A 't Hoen
    Department of Pediatric Urology, Erasmus MC University Medical Center, Rotterdam-Sophia Children's Hospital, Rotterdam, The Netherlands. Electronic address: l.thoen@erasmusmc.nl.
  • Daniel T Keefe
    Division of Urology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
  • Caleb P Nelson
    Clinical and Health Services Research, Department of Urology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, USA.
  • Bernarda Viteri
    Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Hsin-Hsiao Scott Wang
    Department of Urology, Boston Children's Hospital, Boston, MA, USA.
  • John Weaver
    Division of Urology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104, USA.
  • Priyank Yadav
    Department of Urology and Renal Transplant, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India.
  • Armando J Lorenzo
    Department of Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.