New Insights Into the Correlation Between Necroptotic Activation and Neutrophil Infiltration in Pulpitis.

Journal: International dental journal
Published Date: Mar 25, 2025

Abstract

BACKGROUND: Pulpitis is a significant dental concern characterized by inflammation of the dental pulp, often causing severe pain and potential tooth loss. Immune infiltration and necroptosis, both implicated in various inflammatory conditions, have been noted in pulpitis. However, the roles of necroptosis and immune infiltration in pulpitis pathogenesis remain poorly understood.

Authors

  • Xiaolan Guo
    Shenzhen Clinical College of Stomatology, School of Stomatology, Southern Medical University, Shenzhen, People's Republic of China; Shenzhen Stomatology Hospital (Pingshan) of Southern Medical University, Shenzhen, People's Republic of China.
  • Xinyan Ma
    School of Science, Xi'an Polytechnic University, Xi'an, 710048, P.R. China.
  • Peng Liu
    Department of Clinical Pharmacy, Dazhou Central Hospital, Dazhou 635000, China.
  • Xiaoxin Chen
    Guangdong Zhongsheng Pharmaceutical Co., Ltd., Dongguan, Guangdong 523325, China.
  • Sitong Liu
    Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
  • Longrui Dang
    Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
  • Buling Wu
    Shenzhen Clinical College of Stomatology, School of Stomatology, Southern Medical University, Shenzhen, People's Republic of China; Shenzhen Stomatology Hospital (Pingshan) of Southern Medical University, Shenzhen, People's Republic of China; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China. Electronic address: bulingwu@smu.edu.cn.
  • Zhao Chen

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