MVT-Net: A novel cervical tumour segmentation using multi-view feature transfer learning.

Journal: PloS one
Published Date:

Abstract

Cervical cancer is one of the most aggressive malignant tumours of the reproductive system, posing a significant global threat to women's health. Accurately segmenting cervical tumours in MR images remains a challenging task due to the complex characteristics of tumours and the limitations of traditional methods. To address these challenges, this study proposes a novel cervical tumour segmentation model based on multi-view feature transfer learning, named MVT-Net. The model integrates a 2D global axial plane encoder-decoder network and a 3D multi-scale segmentation network as source and target domains, respectively. A transfer learning strategy is employed to extract diverse tumour-related information from multiple perspectives. In addition, a multi-scale residual blocks and a multi-scale residual attention blocks are embedded in the 3D network to effectively capture feature correlations across channels and spatial positions. Experiments on a cervical MR dataset of 160 images show that our proposed MVT-Net outperforms state-of-the-art methods, achieving a DICE score of [Formula: see text], an ASD of [Formula: see text] mm and superior performance in tumour localisation, shape delineation and edge segmentation. Ablation studies further validate the effectiveness of the proposed multi-view feature transfer strategy. These results demonstrate that our proposed MVT-Net represents a significant advance in cervical tumour segmentation, offering improved accuracy and reliability in clinical applications.

Authors

  • Yao Yao
    Key Laboratory for Organic Electronics and Information Displays (KLOEID) & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China.
  • Yunzhi Chen
    School of Information Engineering, Hangzhou Vocational & Technical College, Hangzhou, China.
  • An Yang
    School of Information Engineering, Hangzhou Vocational and Technical College, Hangzhou, Zhejiang, China.
  • Ye Ye
    Department of Biomedical Informatics, University of Pittsburgh School of Medicine, 5607 Baum Boulevard, Pittsburgh, PA, United States; Intelligent System Program, University of Pittsburgh Dietrich School of Arts and Sciences, 210 South Bouquet Street, Pittsburgh, PA, United States.
  • Lichun Wei
    Department of Radiation Oncology, the First Affiliated Hospital of Air Force Medical University, Xi'an, Shaanxi, China.
  • Shuiping Gou
    Key Lab of Intelligent Perception and Image Understanding of Ministry of Education, Xidian University, Xi'an, Shaanxi, 710071, China.
  • Hua Yang