LoopIng: a template-based tool for predicting the structure of protein loops.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Aug 6, 2015
Abstract
MOTIVATION: Predicting the structure of protein loops is very challenging, mainly because they are not necessarily subject to strong evolutionary pressure. This implies that, unlike the rest of the protein, standard homology modeling techniques are not very effective in modeling their structure. However, loops are often involved in protein function, hence inferring their structure is important for predicting protein structure as well as function.