AIMC Topic: Software

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PyNoetic: A modular python framework for no-code development of EEG brain-computer interfaces.

PloS one
Electroencephalography (EEG)-based Brain-Computer Interfaces (BCIs) have emerged as a transformative technology with applications spanning robotics, virtual reality, medicine, and rehabilitation. However, existing BCI frameworks face several limitati...

varCADD: large sets of standing genetic variation enable genome-wide pathogenicity prediction.

Genome medicine
BACKGROUND: Machine learning and artificial intelligence are increasingly being applied to identify phenotypically causal genetic variation. These data-driven methods require comprehensive training sets to deliver reliable results. However, large unb...

Semi-supervised contrastive learning variational autoencoder Integrating single-cell multimodal mosaic datasets.

BMC bioinformatics
As single-cell sequencing technology became widely used, scientists found that single-modality data alone could not fully meet the research needs of complex biological systems. To address this issue, researchers began simultaneously collect multi-mod...

Apax: A Flexible and Performant Framework for the Development of Machine-Learned Interatomic Potentials.

Journal of chemical information and modeling
We introduce Atomistic learned potentials in JAX (apax), a flexible and efficient open source software package for training and inference of machine-learned interatomic potentials. Built on the JAX framework, apax supports GPU acceleration and implem...

PuMA: PubMed gene/cell type-relation Atlas.

BMC bioinformatics
BACKGROUND: Rapid extraction and visualization of cell-specific gene expression is important for automatic cell type annotation, e.g. in single cell analysis. There is an emerging field in which tools such as curated databases or machine learning met...

Prediction of hub genes in pulpal inflammation and regeneration using autoencoders and a generative AI approach.

Scientific reports
Pulpal inflammation and regeneration are crucial for enhancing endodontic treatment outcomes. Transcriptomic studies highlight the involvement of proinflammatory cytokines, NF-κB signaling, and stem cell activity. This study employs a generative AI a...

Evaluation of the False Discovery Rate in Library-Free Search by DIA-NN Using Human Proteome.

Journal of proteome research
Recently, deep-learning-based spectral libraries have gained increasing attention. Several data-independent acquisition (DIA) software tools have integrated this feature, known as a library-free search, thereby making DIA analysis more accessible. H...

Metagenomics-Toolkit: the flexible and efficient cloud-based metagenomics workflow featuring machine learning-enabled resource allocation.

NAR genomics and bioinformatics
The metagenome analysis of complex environments with thousands of datasets, such as those in the Sequence Read Archive, requires substantial computational resources for it to be completed within a reasonable time frame. Efficient use of infrastructur...

Statistical toolkit for analysis of radiotherapy DICOM data.

Biomedical physics & engineering express
Radiotherapy (RT) has become increasingly sophisticated, necessitating advanced tools for analyzing extensive treatment data in hospital databases. Such analyses can enhance future treatments, particularly through Knowledge-Based Planning, and aid in...

Cross-attention graph neural networks for inferring gene regulatory networks with skewed degree distribution.

BMC bioinformatics
BACKGROUND: Inferring Gene Regulatory Networks (GRNs) from gene expression data is a pivotal challenge in systems biology. Most existing methods fail to consider the skewed degree distribution of genes, complicating the application of directed graph ...