Nonlocal atlas-guided multi-channel forest learning for human brain labeling.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: It is important for many quantitative brain studies to label meaningful anatomical regions in MR brain images. However, due to high complexity of brain structures and ambiguous boundaries between different anatomical regions, the anatomical labeling of MR brain images is still quite a challenging task. In many existing label fusion methods, appearance information is widely used. However, since local anatomy in the human brain is often complex, the appearance information alone is limited in characterizing each image point, especially for identifying the same anatomical structure across different subjects. Recent progress in computer vision suggests that the context features can be very useful in identifying an object from a complex scene. In light of this, the authors propose a novel learning-based label fusion method by using both low-level appearance features (computed from the target image) and high-level context features (computed from warped atlases or tentative labeling maps of the target image).

Authors

  • Guangkai Ma
    Space Control and Inertial Technology Research Center, Harbin Institute of Technology, Harbin 150001, China and Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
  • Yaozong Gao
  • Guorong Wu
    Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Ligang Wu
  • Dinggang Shen
    School of Biomedical Engineering, ShanghaiTech University, Shanghai, China.