Rectified-Linear-Unit-Based Deep Learning for Biomedical Multi-label Data.

Journal: Interdisciplinary sciences, computational life sciences
Published Date:

Abstract

Disease diagnosis is one of the major data mining questions by the clinicians. The current diagnosis models usually have a strong assumption that one patient has only one disease, i.e. a single-label data mining problem. But the patients, especially when at the late stages, may have more than one disease and require a multi-label diagnosis. The multi-label data mining is much more difficult than a single-label one, and very few algorithms have been developed for this situation. Deep learning is a data mining algorithm with highly dense inner structure and has achieved many successful applications in the other areas. We propose a hypothesis that rectified-linear-unit-based deep learning algorithm may also be good at the clinical questions, by revising the last layer as a multi-label output. The proof-of-concept experimental data support the hypothesis, and the community may be interested in trying more applications.

Authors

  • Pu Wang
    Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
  • Ruiquan Ge
  • Xuan Xiao
    Computer Department, Jingdezhen Ceramic Institute, Jingdezhen 333046, China.
  • Yunpeng Cai
    Shenzhen Institutes of Advanced Technology, and Key Lab for Health Informatics, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, People's Republic of China. yp.cai@siat.ac.cn.
  • Guoqing Wang
    Department of Pathogenobiology, Basic Medical College of Jilin University, Changchun, Jilin, 130012, People's Republic of China. qing@jlu.edu.cn.
  • Fengfeng Zhou