Prediction of Adverse Events in Patients Undergoing Major Cardiovascular Procedures.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

Electronic health records (EHR) provide opportunities to leverage vast arrays of data to help prevent adverse events, improve patient outcomes, and reduce hospital costs. This paper develops a postoperative complications prediction system by extracting data from the EHR and creating features. The analytic engine then provides model accuracy, calibration, feature ranking, and personalized feature responses. This allows clinicians to interpret the likelihood of an adverse event occurring, general causes for these events, and the contributing factors for each specific patient. The patient cohort considered was 5214 patients in Yale-New Haven Hospital undergoing major cardiovascular procedures. Cohort-specific models predicted the likelihood of postoperative respiratory failure and infection, and achieved an area under the receiver operating characteristic curve of 0.81 for respiratory failure and 0.83 for infection.

Authors

  • Bobak J Mortazavi
    Texas A&M University, USA.
  • Nihar Desai
  • Jing Zhang
    MOEMIL Laboratory, School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu, China.
  • Andreas Coppi
  • Fred Warner
  • Harlan M Krumholz
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Sahand Negahban