Using a Multi-Task Recurrent Neural Network With Attention Mechanisms to Predict Hospital Mortality of Patients.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

Estimating hospital mortality of patients is important in assisting clinicians to make decisions and hospital providers to allocate resources. This paper proposed a multi-task recurrent neural network with attention mechanisms to predict patients' hospital mortality, using reconstruction of patients' physiological time series as an auxiliary task. Experiments were conducted on a large public electronic health record database, i.e., MIMIC-III. Fifteen physiological measurements during the first 24 h of critical care were used to predict death before hospital discharge. Compared with the conventional simplified acute physiology score (SAPS-II), the proposed multi-task learning model achieved better sensitivity (0.503 ± 0.020 versus 0.365 ± 0.021), when predictions were made based on the same 24-h observation period. The multi-task learning model is recommended to be updated daily with at least a 6-h observation period, in order for it to perform similarly or better than the SAPS-II. In the future, the need for intervention can be considered as another task to further optimize the performance of the multi-task learning model.

Authors

  • Ruoxi Yu
    National Institute of Traditional Chinese Medicine Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing, China.
  • Yali Zheng
  • Ruikai Zhang
  • Yuqi Jiang
  • Carmen C Y Poon
    CUHK Jockey Club Minimally Invasive Surgical Skills Center, The Chinese University of Hong Kong, Shatin, Hong Kong.