Prediction of activity and specificity of CRISPR-Cpf1 using convolutional deep learning neural networks.
Journal:
BMC bioinformatics
Published Date:
Jun 13, 2019
Abstract
BACKGROUND: CRISPR-Cpf1 has recently been reported as another RNA-guided endonuclease of class 2 CRISPR-Cas system, which expands the molecular biology toolkit for genome editing. However, most of the online tools and applications to date have been developed primarily for the Cas9. There are a limited number of tools available for the Cpf1.