Research Progress of Metabolomics Techniques Combined with Machine Learning Algorithm in Wound Age Estimation.

Journal: Fa yi xue za zhi
PMID:

Abstract

Wound age estimation is the core content in the practice of forensic medicine. Accurate estimation of wound age is a scientific question that needs to be urgently solved by forensic scientists at home and abroad. Metabolomics techniques can effectively detect endogenous metabolites produced by internal or external stimulating factors and describe the dynamic changes of metabolites . It has the advantages of strong operability, high detection efficiency and accurate quantitative results. Machine learning algorithm has special advantages in processing high-dimensional data sets, which can effectively mine biological information and truly reflect the physiological, disease or injury state of the body. It is a new technical means for efficiently processing high-throughput big data. This paper reviews the status and advantages of metabolomic techniques combined with machine learning algorithm in the research of wound age estimation, and provides new ideas for this research.

Authors

  • Xing-Yu Ma
    Collaborative Innovation Center of Judicial Civilization, Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100088, China.
  • Hao Cheng
    Department of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang 110122, China.
  • Zhong-Duo Zhang
    Department of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang 110122, China.
  • Ye-Ming Li
    Collaborative Innovation Center of Judicial Civilization, Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100088, China.
  • Dong Zhao
    Collaborative Innovation Center of Judicial Civilization, Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100088, China.