Release of Hyaluronan in Aneurysmal Subarachnoid Hemorrhage and Cerebral Vasospasm: A Pilot Study Indicating a Shedding of the Endothelial Glycocalyx.

Journal: Journal of neurosurgical anesthesiology
Published Date: Oct 28, 2021

Abstract

BACKGROUND: This pilot study investigated plasma concentrations of hyaluronan, heparan sulfate, and syndecan-1 as possible biomarkers for glycocalyx integrity after aneurysmal subarachnoid hemorrhage (aSAH).

Authors

  • Volker C Schick
    Departments of Anesthesiology and Intensive Care Medicine.
  • Tobias Neumann
    Departments of Anesthesiology and Intensive Care Medicine.
  • Anja Illerhaus
    Dermatology.
  • Marco Timmer
    Neurosurgery, Faculty of Medicine and University Hospital Cologne, University of Cologne.
  • Alexander Fuchs
    Department of Periodontology, Endodontology and Cariology, University Center for Dental Medicine Basel UZB, University of Basel, Basel, Switzerland. [email protected].
  • Stefan Grau
    Neurosurgery, Faculty of Medicine and University Hospital Cologne, University of Cologne.
  • Thorsten Annecke
    Departments of Anesthesiology and Intensive Care Medicine.

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