PconsC4: fast, accurate and hassle-free contact predictions.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Residue contact prediction was revolutionized recently by the introduction of direct coupling analysis (DCA). Further improvements, in particular for small families, have been obtained by the combination of DCA and deep learning methods. However, existing deep learning contact prediction methods often rely on a number of external programs and are therefore computationally expensive.

Authors

  • Mirco Michel
    Science for Life Laboratory and Department of Biochemistry and Biophysics, Stockholm University, Stockholm 10691, Sweden.
  • David Menéndez Hurtado
    Department of Biochemistry and Biophysics and Science for Life Laboratory, Stockholm University, Solna, Sweden.
  • Arne Elofsson
    Science for Life Laboratory and Department of Biochemistry and Biophysics, Stockholm University, Stockholm 10691, Sweden arne@bioinfo.se debbie@hms.harvard.edu cccsander@gmail.com.