ResPRE: high-accuracy protein contact prediction by coupling precision matrix with deep residual neural networks.

Journal: Bioinformatics (Oxford, England)
Published Date: Nov 1, 2019

Abstract

MOTIVATION: Contact-map of a protein sequence dictates the global topology of structural fold. Accurate prediction of the contact-map is thus essential to protein 3D structure prediction, which is particularly useful for the protein sequences that do not have close homology templates in the Protein Data Bank.

Authors

  • Yang Li
    Occupation of Chinese Center for Disease Control and Prevention, Beijing, China.
  • Jun Hu
    Jinling Clinical Medical College, Nanjing Medical University，Nanjing，Jiangsu 210002，China.
  • Chengxin Zhang
    Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.
  • Dong-Jun Yu
  • Yang Zhang
    Innovative Institute of Chinese Medicine and Pharmacy, Academy for Interdiscipline, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

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