Using Reduced Amino Acid Alphabet and Biological Properties to Analyze and Predict Animal Neurotoxin Protein.

Journal: Current drug metabolism
Published Date:

Abstract

AIMS: Because of the high affinity of these animal neurotoxin proteins for some special target site, they were usually used as pharmacological tools and therapeutic agents in medicine to gain deep insights into the function of the nervous system.

Authors

  • Yao Yu
    AbbVie Inc, North Chicago, IL, USA.
  • Shiyuan Wang
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China.
  • Yakun Wang
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China.
  • Yiyin Cao
    Public Health College, Harbin Medical University, Harbin 150081, China.
  • Chunlu Yu
    Public Health College, Harbin Medical University, Harbin 150081, China.
  • Yi Pan
    Department of Neurosis and Psychosomatic Diseases, Huzhou Third Municipal Hospital, The Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, China.
  • Dongqing Su
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China.
  • Qianzi Lu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China.
  • Yongchun Zuo
    The State key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
  • Lei Yang
    George Mason University.