Retinal blood vessel segmentation based on Densely Connected U-Net.

Journal: Mathematical biosciences and engineering : MBE
Published Date:

Abstract

The segmentation of blood vessels from retinal images is an important and challenging task in medical analysis and diagnosis. This paper proposes a new architecture of the U-Net network for retinal blood vessel segmentation. Adding dense block to U-Net network makes each layer's input come from the all previous layer's output which improves the segmentation accuracy of small blood vessels. The effectiveness of the proposed method has been evaluated on two public datasets (DRIVE and CHASE_DB1). The obtained results (DRIVE: Acc = 0.9559, AUC = 0.9793, CHASE_DB1: Acc = 0.9488, AUC = 0.9785) demonstrate the better performance of the proposed method compared to the state-of-the-art methods. Also, the results show that our method achieves better results for the segmentation of small blood vessels and can be helpful to evaluate related ophthalmic diseases.

Authors

  • Yin Lin Cheng
    School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 510006, China.
  • Meng Nan Ma
    School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 510006, China.
  • Liang Jun Zhang
    School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 510006, China.
  • Chen Jin Jin
    Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510006, China.
  • Li Ma
    Department of Technological Research and Development, Hunan Guanmu Biotech Co., Ltd, Changsha, China.
  • Yi Zhou
    Eye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.