CT window trainable neural network for improving intracranial hemorrhage detection by combining multiple settings.

Journal: Artificial intelligence in medicine
Published Date:

Abstract

Window settings to rescale and contrast stretch raw data from radiographic images such as Computed Tomography (CT), X-ray and Magnetic Resonance images is a crucial step as data pre-processing to examine abnormalities and diagnose diseases. We propose a distant-supervised method for determining automatically the best window settings by attaching a window estimator module (WEM) to a deep convolutional neural network (DCNN)-based lesion classifier and training them in conjunction. Aside from predicting a flexible window setting for each raw image, we statistically identify the top four window settings by calculating the mean and standard deviations for the entire dataset. Images are scaled on each of the top settings estimated by WEM and following lesion classifiers are subsequently trained. We study the effects of only using the flexible window, the single fixed window as either a known default window used by radiologists or an estimated mean value, and two different approaches to combine results from the top window settings to improve the detection of intracranial hemorrhage (ICH) from brain CT images. Experimental results showed that using the top four window settings identified from the window estimator module and combining the results had the best performance.

Authors

  • Manohar Karki
    Louisiana State University, Baton Rouge, LA, USA.
  • Junghwan Cho
    CAIDE Systems Inc., 110 Canal St., Lowell, MA, 01852, USA. jcho@caidesystems.com.
  • Eunmi Lee
    CAIDE Systems Inc., 110 Canal St., Lowell, MA, 01852, USA.
  • Myong-Hun Hahm
    Department of Radiology, School of Medicine, Kyungpook National University, South Korea. Electronic address: hammh7@gmail.com.
  • Sang-Youl Yoon
    Department of Neurosurgery, School of Medicine, Kyungpook National University, Daegu, South Korea. Electronic address: customplus@naver.com.
  • Myungsoo Kim
    Department of Neurosurgery, School of Medicine of Kyungpook National University, 680 Gukchaebosang-ro, Jung-gu, Daegu, 41944, South Korea.
  • Jae-Yun Ahn
    Department of Emergency Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea. Electronic address: portnoy27@hanmail.net.
  • Jeongwoo Son
    Department of Emergency Medicine, School of Medicine of Kyungpook National University, 680 Gukchaebosang-ro, Jung-gu, Daegu, 41944, South Korea.
  • Shin-Hyung Park
    Department of Radiation Oncology, School of Medicine, Kyungpook National University, South Korea. Electronic address: shinhyungpark@knu.ac.kr.
  • Ki-Hong Kim
    Department of Neurosurgery, School of Medicine of Daegu Catholic University, Daegu, South Korea. Electronic address: gneuros@cu.ac.kr.
  • Sinyoul Park
    Department of Emergency Medicine, College of Medicine of Yeungnam University, 317-1 Daemyung-dong, Nam-gu, Daegu, 705-717, South Korea.