Implementing machine learning methods for imaging flow cytometry.

Journal: Microscopy (Oxford, England)
Published Date:

Abstract

In this review, we focus on the applications of machine learning methods for analyzing image data acquired in imaging flow cytometry technologies. We propose that the analysis approaches can be categorized into two groups based on the type of data, raw imaging signals or features explicitly extracted from images, being analyzed by a trained model. We hope that this categorization is helpful for understanding uniqueness, differences and opportunities when the machine learning-based analysis is implemented in recently developed 'imaging' cell sorters.

Authors

  • Sadao Ota
    Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
  • Issei Sato
    Department of Complexity Science and Engineering, The University of Tokyo, Japan; Department of Computer Science, The University of Tokyo, Japan; Center for Advanced Intelligence Project, RIKEN, Japan. Electronic address: sato@k.u-tokyo.ac.jp.
  • Ryoichi Horisaki