Multilevel approach to male fertility by machine learning highlights a hidden link between haematological and spermatogenetic cells.

Journal: Andrology
PMID:

Abstract

BACKGROUND: Male infertility represents a complex clinical condition requiring an accurate multilevel assessment, in which machine learning technology, combining large data series in non-linear and highly interactive ways, could be innovatively applied.

Authors

  • Daniele Santi
    Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Giorgia Spaggiari
    Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy.
  • Andrea Casonati
    Hopenly S.r.l., Vignola, Modena, Italy.
  • Livio Casarini
    Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Roberto Grassi
    Department of Radiology, University of Campania "L. Vanvitelli", Naples, Italy.
  • Barbara Vecchi
    Hopenly S.r.l., Vignola, Modena, Italy.
  • Laura Roli
    Department of Laboratory Medicine and Anatomy Pathology, Azienda USL of Modena, Modena, Italy.
  • Maria Cristina De Santis
    Department of Laboratory Medicine and Anatomy Pathology, Azienda USL of Modena, Modena, Italy.
  • Giovanna Orlando
    Medical Affair Fertility, Merck-Serono S.p.a, Rome, Italy.
  • Enrica Gravotta
    Medical Affairs Fertility EMEA, Merck KGaA, Darmstadt, Germany.
  • Enrica Baraldi
    Department of Laboratory Medicine and Anatomy Pathology, Azienda USL of Modena, Modena, Italy.
  • Monica Setti
    Service of Clinical Engineering, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy.
  • Tommaso Trenti
    Department of Laboratory Medicine and Anatomy Pathology, Azienda USL of Modena, Modena, Italy.
  • Manuela Simoni
    Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.