PPTPP: a novel therapeutic peptide prediction method using physicochemical property encoding and adaptive feature representation learning.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Jul 1, 2020
Abstract
MOTIVATION: Peptide is a promising candidate for therapeutic and diagnostic development due to its great physiological versatility and structural simplicity. Thus, identifying therapeutic peptides and investigating their properties are fundamentally important. As an inexpensive and fast approach, machine learning-based predictors have shown their strength in therapeutic peptide identification due to excellences in massive data processing. To date, no reported therapeutic peptide predictor can perform high-quality generic prediction and informative physicochemical properties (IPPs) identification simultaneously.