Frequency spectra characterization of noncoding human genomic sequences.

Journal: Genes & genomics
Published Date: Oct 1, 2020

Abstract

BACKGROUND: Noncoding sequences have been demonstrated to possess regulatory functions. Its classification is challenging because they do not show well-defined nucleotide patterns that can correlate with their biological functions. Genomic signal processing techniques like Fourier transform have been employed to characterize coding and noncoding sequences. This transformation in a systematic whole-genome noncoding library, such as the ENCODE database, can provide evidence of a periodic behaviour in the noncoding sequences that correlates with their regulatory functions.

Authors

  • O Paredes
    Computer Sciences Department, Universidad de Guadalajara, Guadalajara, Mexico.
  • Rebeca Romo-Vázquez
    Computer Sciences Department, Universidad de Guadalajara, Guadalajara, Mexico.
  • Israel Román-Godínez
    Computer Sciences Department, Universidad de Guadalajara, Guadalajara, Mexico.
  • Hugo Vélez-Pérez
    Computer Sciences Department, Universidad de Guadalajara, Guadalajara, Mexico.
  • Ricardo A Salido-Ruiz
    Computer Sciences Department, Universidad de Guadalajara, Guadalajara, Mexico.
  • J Alejandro Morales
    Computer Sciences Department, Universidad de Guadalajara, Guadalajara, Mexico. jalejandro.morales@academicos.udg.mx.

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