Prospective Deployment of Deep Learning in MRI: A Framework for Important Considerations, Challenges, and Recommendations for Best Practices.

Journal: Journal of magnetic resonance imaging : JMRI
Published Date:

Abstract

Artificial intelligence algorithms based on principles of deep learning (DL) have made a large impact on the acquisition, reconstruction, and interpretation of MRI data. Despite the large number of retrospective studies using DL, there are fewer applications of DL in the clinic on a routine basis. To address this large translational gap, we review the recent publications to determine three major use cases that DL can have in MRI, namely, that of model-free image synthesis, model-based image reconstruction, and image or pixel-level classification. For each of these three areas, we provide a framework for important considerations that consist of appropriate model training paradigms, evaluation of model robustness, downstream clinical utility, opportunities for future advances, as well recommendations for best current practices. We draw inspiration for this framework from advances in computer vision in natural imaging as well as additional healthcare fields. We further emphasize the need for reproducibility of research studies through the sharing of datasets and software. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY STAGE: 2.

Authors

  • Akshay S Chaudhari
    Department of Radiology, Stanford University, Stanford, California.
  • Christopher M Sandino
    Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, CA.
  • Elizabeth K Cole
    Department of Radiology, Stanford University, Stanford, California, USA.
  • David B Larson
    Department of Radiology, Warren Alpert Medical School, Brown University, 593 Eddy St, Providence, RI 02903 (I.P.); Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI (I.P.); Visiana, Hørsholm, Denmark (H.H.T.); Department of Radiology, Stanford University, Palo Alto, Calif (S.S.H., D.B.L.); and Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (J.K.C.).
  • Garry E Gold
    Department of Radiology, Stanford University, Stanford, California.
  • Shreyas S Vasanawala
  • Matthew P Lungren
  • Brian A Hargreaves
    Department of Radiology, Stanford University, Stanford, California.
  • Curtis P Langlotz
    Stanford University, University Medical Line, Stanford, CA, 94305, US.