T1 and T2 MR fingerprinting measurements of prostate cancer and prostatitis correlate with deep learning-derived estimates of epithelium, lumen, and stromal composition on corresponding whole mount histopathology.

Abstract

Authors

• Rakesh Shiradkar
  Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH, 44106, USA.
• Ananya Panda
  Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
• Patrick Leo
  Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio.
• Andrew Janowczyk
  Biomedical Engineering Department, Case Western Reserve University, Cleveland, Ohio.
• Xavier Farré
  Department of Health, Public Health Agency of Catalonia, Lleida, Catalonia, Spain.
• Nafiseh Janaki
  Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
• Lin Li
  Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.
• Shivani Pahwa
  Department of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
• Amr Mahran
  Department of Urology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
• Christina Buzzy
  Department of Urology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
• Pingfu Fu
  Department of Biomedical Engineering, Case Western Reserve University School of Engineering, 2071 Martin Luther King Dr, Cleveland, OH 44106-7207 (M. Khorrami, K.B., A.M.); Departments of Internal Medicine (M. Khunger) and Solid Tumor Oncology (A.Z., P.P.), Cleveland Clinic, Cleveland, Ohio; Department of Internal Medicine, Maimonides Medical Center, Brooklyn, NY (R.T.); Department of Radiology, UT Southwestern Medical Center, Dallas, Tex (P.R.); Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio (P.F.); Department of Hematology and Oncology, New York University, New York, NY (V.V.); Louis Stokes Cleveland Veterans Administration Medical Center, Cleveland, Ohio (A.M.).
• Robin Elliott
  Department of Pathology, Case Western Reserve University, Cleveland, Ohio.
• Gregory MacLennan
  Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
• Lee Ponsky
  University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio.
• Vikas Gulani
  Department of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
• Anant Madabhushi
  Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio.

Keywords

External Resources