ELNet:Automatic classification and segmentation for esophageal lesions using convolutional neural network.

Journal: Medical image analysis
Published Date:

Abstract

Automatic and accurate esophageal lesion classification and segmentation is of great significance to clinically estimate the lesion statuses of the esophageal diseases and make suitable diagnostic schemes. Due to individual variations and visual similarities of lesions in shapes, colors, and textures, current clinical methods remain subject to potential high-risk and time-consumption issues. In this paper, we propose an Esophageal Lesion Network (ELNet) for automatic esophageal lesion classification and segmentation using deep convolutional neural networks (DCNNs). The underlying method automatically integrates dual-view contextual lesion information to extract global features and local features for esophageal lesion classification and lesion-specific segmentation network is proposed for automatic esophageal lesion annotation at pixel level. For the established clinical large-scale database of 1051 white-light endoscopic images, ten-fold cross-validation is used in method validation. Experiment results show that the proposed framework achieves classification with sensitivity of 0.9034, specificity of 0.9718, and accuracy of 0.9628, and the segmentation with sensitivity of 0.8018, specificity of 0.9655, and accuracy of 0.9462. All of these indicate that our method enables an efficient, accurate, and reliable esophageal lesion diagnosis in clinics.

Authors

  • Zhan Wu
    School of Cyberspace Security, Southeast University, Nanjing, Jiangsu, China.
  • Rongjun Ge
    Laboratory of Image Science and Technology, School of Computer Science and Engineering, Southeast University, Nanjing, China; Key Laboratory of Computer Network and Information Integration (Southeast University), Ministry of Education, Nanjing, China; Centre de Recherche en Information Biomedicale Sino-Francais (LIA CRIBs), Rennes, France.
  • Minli Wen
    School of Cyberspace Security, Southeast University, Nanjing, Jiangsu, China.
  • Gaoshuang Liu
    Department of Geriatric Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Yang Chen
    Orthopedics Department of the First Affiliated Hospital of Tsinghua University, Beijing, China.
  • Pinzheng Zhang
    School of Computer Science and Engineering, Southeast University, Nanjing, Jiangsu, China.
  • Xiaopu He
    Department of Geriatric Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: help@njmu.edu.cn.
  • Jie Hua
    Department of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Limin Luo
  • Shuo Li
    Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.