Timely Diagnosis of Acute Lymphoblastic Leukemia Using Artificial Intelligence-Oriented Deep Learning Methods.

Journal: Computational intelligence and neuroscience
Published Date:

Abstract

BACKGROUND: Leukemia is fatal cancer in both children and adults and is divided into acute and chronic. Acute lymphoblastic leukemia (ALL) is a subtype of this cancer. Early diagnosis of this disease can have a significant impact on the treatment of this disease. Computational intelligence-oriented techniques can be used to help physicians identify and classify ALL rapidly. . In this study, the utilized dataset was collected from a CodaLab competition to classify leukemic cells from normal cells in microscopic images. Two famous deep learning networks, including residual neural network (ResNet-50) and VGG-16 were employed. These two networks are already trained by our assigned parameters, meaning we did not use the stored weights; we adjusted the weights and learning parameters too. Also, a convolutional network with ten convolutional layers and 22 max-pooling layers-with strides 2-was proposed, and six common machine learning techniques were developed to classify acute lymphoblastic leukemia into two classes.

Authors

  • Sorayya Rezayi
    Department of Health Information Management and Medical Informatics, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
  • Niloofar Mohammadzadeh
    Department of Health Information Management, Tehran University of Medical Sciences, Tehran, Iran.
  • Hamid Bouraghi
    Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
  • Soheila Saeedi
    Department of Health Information Management & Technology, School of Allied Health Professions, Kashan University of Medical Sciences, Kashan, Iran; Student research committee, Kashan University of Medical sciences, Kashan, Iran.
  • Ali Mohammadpour
    Department of Health Information Technology, School of Allied Medical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.