ToxDL: deep learning using primary structure and domain embeddings for assessing protein toxicity.

Journal: Bioinformatics (Oxford, England)
Published Date: Jan 29, 2021

Abstract

MOTIVATION: Genetically engineering food crops involves introducing proteins from other species into crop plant species or modifying already existing proteins with gene editing techniques. In addition, newly synthesized proteins can be used as therapeutic protein drugs against diseases. For both research and safety regulation purposes, being able to assess the potential toxicity of newly introduced/synthesized proteins is of high importance.

Authors

  • Xiaoyong Pan
    Department of Veterinary Clinical and Animal Sciences, University of Copenhagen, Copenhagen, Denmark. xypan172436@gmail.com.
  • Jasper Zuallaert
    Center for Biotech Data Science, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University Global Campus, Songdo, Incheon, South Korea.
  • Xi Wang
    School of Information, Central University of Finance and Economics, Beijing, China.
  • Hong-Bin Shen
    Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China. hbshen@sjtu.edu.cn.
  • Elda Posada Campos
    BASF Belgium Coordination Center - Innovation Center Gent, Ghent 9000, Belgium.
  • Denys O Marushchak
    BASF Belgium Coordination Center - Innovation Center Gent, Ghent 9000, Belgium.
  • Wesley De Neve
    Center for Biotech Data Science, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University Global Campus, Songdo, Incheon, South Korea.

Keywords

External Resources

Popular Topics
Recent Journals