Predicting drug-disease associations through layer attention graph convolutional network.

Journal: Briefings in bioinformatics
Published Date:

Abstract

BACKGROUND: Determining drug-disease associations is an integral part in the process of drug development. However, the identification of drug-disease associations through wet experiments is costly and inefficient. Hence, the development of efficient and high-accuracy computational methods for predicting drug-disease associations is of great significance.

Authors

  • Zhouxin Yu
    College of Informatics, Huazhong Agricultural University.
  • Feng Huang
    Beijing Hospital of TCM, Capital Medical University, Beijing 100010, China; Institution of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700.
  • Xiaohan Zhao
    College of Informatics, Huazhong Agricultural University.
  • Wenjie Xiao
    University of Washington.
  • Wen Zhang
    Oil Crops Research Institute, Chinese Academy of Agricultural Sciences Wuhan 430062 China peiwuli@oilcrops.cn zhangqi521x@126.com +86-27-8681-2943 +86-27-8671-1839.