Overview of featurization techniques used in traditional versus emerging deep learning-based algorithms for automated interpretation of the 12-lead ECG.

Journal: Journal of electrocardiology
Published Date:

Abstract

Automated interpretation of the 12-lead ECG has remained an underpinning interest in decades of research that has seen a diversity of computing applications in cardiology. The application of computers in cardiology began in the 1960s with early research focusing on the conversion of analogue ECG signals (voltages) to digital samples. Alongside this, software techniques that automated the extraction of wave measurements and provided basic diagnostic statements, began to emerge. In the years since then there have been many significant milestones which include the widespread commercialisation of 12-lead ECG interpretation software, associated clinical utility and the development of the related regulatory frameworks to promote standardised development. In the past few years, the research community has seen a significant rejuvenation in the development of ECG interpretation programs. This is evident in the research literature where a large number of studies have emerged tackling a variety of automated ECG interpretation problems. This is largely due to two factors. Specifically, the technical advances, both software and hardware, that have facilitated the broad adoption of modern artificial intelligence (AI) techniques, and, the increasing availability of large datasets that support modern AI approaches. In this article we provide a very high-level overview of the operation of and approach to the development of early 12-lead ECG interpretation programs and we contrast this to the approaches that are now seen in emerging AI approaches. Our overview is mainly focused on highlighting differences in how input data are handled prior to generation of the diagnostic statement.

Authors

  • Dewar Finlay
    Nanotechnology and Integrated Bioengineering Centre, Ulster University, Jordanstown, Northern Ireland, United Kingdom.
  • Raymond Bond
    Ulster University, School of Computing, York St, Northern Ireland.
  • Michael Jennings
    Faculty of Computing, Engineering and the Built Environment, Ulster University, Jordanstown Campus, Northern Ireland, UK.
  • Christopher McCausland
    Faculty of Computing, Engineering and the Built Environment, Ulster University, Jordanstown Campus, Northern Ireland, UK.
  • Daniel Guldenring
    HTW Berlin, Wilhelminenhofstr. 75A, 12459 Berlin, Germany.
  • Alan Kennedy
    PulseAI, Belfast, United Kingdom.
  • Pardis Biglarbeigi
    Faculty of Computing, Engineering and the Built Environment, Ulster University, Jordanstown Campus, Northern Ireland, UK.
  • Salah S Al-Zaiti
    Departments of Acute & Tertiary Care Nursing, Emergency Medicine, and Cardiology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Rob Brisk
    School of Computer Science, Ulster University, Jordanstown, Northern Ireland, United Kingdom; Dept of Cardiology, Craigavon Area Hospital, Craigavon, Northern Ireland, United Kingdom. Electronic address: brisk-r@ulster.ac.uk.
  • James McLaughlin
    Nanotechnology and Integrated Bioengineering Centre, Ulster University, Jordanstown, Northern Ireland, United Kingdom.