Deep Learning vs Traditional Models for Predicting Hospital Readmission among Patients with Diabetes.

Journal: AMIA ... Annual Symposium proceedings. AMIA Symposium
Published Date:

Abstract

A hospital readmission risk prediction tool for patients with diabetes based on electronic health record (EHR) data is needed. The optimal modeling approach, however, is unclear. In 2,836,569 encounters of 36,641 diabetes patients, deep learning (DL) long short-term memory (LSTM) models predicting unplanned, all-cause, 30-day readmission were developed and compared to several traditional models. Models used EHR data defined by a Common Data Model. The LSTM model Area Under the Receiver Operating Characteristic Curve (AUROC) was significantly greater than that of the next best traditional model [LSTM 0.79 vs Random Forest (RF) 0.72, p<0.0001]. Experiments showed that performance of the LSTM models increased as prior encounter number increased up to 30 encounters. An LSTM model with 16 selected laboratory tests yielded equivalent performance to a model with all 981 laboratory tests. This new DL model may provide the basis for a more useful readmission risk prediction tool for diabetes patients.

Authors

  • Ameen A Hai
    Center for Data Analytics and Biomedical Informatics, Philadelphia, PA.
  • Mark G Weiner
    Weill Cornell Medicine, New York, NY.
  • Anuradha Paranjape
    Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
  • Alice Livshits
    Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
  • Jeremiah R Brown
    Departments of Epidemiology and Biomedical Data Science, Dartmouth Geisel School of Medicine, Hanover, New Hampshire.
  • Zoran Obradovic
  • Daniel J Rubin
    Temple University, Philadelphia, PA, United States.