Machine learning for prediction of euploidy in human embryos: in search of the best-performing model and predictive features.

Journal: Fertility and sterility
Published Date:

Abstract

OBJECTIVE: To assess the best-performing machine learning (ML) model and features to predict euploidy in human embryos.

Authors

  • Stefanie De Gheselle
    Department for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address: Stefanie.DeGheselle@UZGENT.be.
  • Céline Jacques
    Apricity, 13 Rue Paul Valéry, 75116 Paris, France.
  • Jérôme Chambost
    Apricity, 13 Rue Paul Valéry, 75116 Paris, France.
  • Celine Blank
    Department of Obstetrics and Gynecology, Catharina Hospital, Eindhoven, the Netherlands; Department of Electrical Engineering (Signal Processing Systems), Eindhoven Technical University, Eindhoven, the Netherlands; Department of Reproductive Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address: celineblank@icloud.com.
  • Klaas Declerck
    Department for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium.
  • Ilse De Croo
    Department for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium.
  • Cristina Hickman
    AI Team, Apricity, 14 Grays Inn Rd, London WC1 X 8HN, UK.; Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0HS, UK.
  • Kelly Tilleman
    Department of Reproductive Medicine, Ghent University Hospital, Ghent, Belgium.