The ethical challenges of artificial intelligence-driven digital pathology.

Journal: The journal of pathology. Clinical research
Published Date:

Abstract

Digital pathology - the digitalisation of clinical histopathology services through the scanning and storage of pathology slides - has opened up new possibilities for health care in recent years, particularly in the opportunities it brings for artificial intelligence (AI)-driven research. Recognising, however, that there is little scholarly debate on the ethics of digital pathology when used for AI research, this paper summarises what it sees as four key ethical issues to consider when deploying AI infrastructures in pathology, namely, privacy, choice, equity, and trust. The themes are inspired from the authors' experience grappling with the challenge of deploying an ethical digital pathology infrastructure to support AI research as part of the National Pathology Imaging Cooperative (NPIC), a collaborative of universities, hospital trusts, and industry partners largely located across the North of England. Though focusing on the UK case, internationally, few pathology departments have gone fully digital, and so the themes developed here offer a heuristic for ethical reflection for other departments currently making a similar transition or planning to do so in the future. We conclude by promoting the need for robust public governance mechanisms in AI-driven digital pathology.

Authors

  • Francis McKay
    The Ethox Centre and the Wellcome Centre for Ethics and Humanities, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Bethany J Williams
    Department of Histopathology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Graham Prestwich
    Patient and Public Engagement Lead, Yorkshire and Humber Academic Health Science Network, Wakefield, UK.
  • Daljeet Bansal
    Department of Histopathology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Nina Hallowell
    Codirector of the EPSRC Centre for Doctoral Training in Health Data Science and a professor at the Ethox Centre and Wellcome Centre for Ethics and Humanities at the University of Oxford.
  • Darren Treanor
    Leeds Teaching Hospitals NHS Trust, Leeds, UK.