The preparation and physicochemical characterization of eprosartan mesylate-laden polymeric ternary solid dispersions for enhanced solubility and dissolution rate of the drug.

Journal: Polimery w medycynie
PMID: 30916494

Abstract

BACKGROUND: Eprosartan mesylate is a poorly water-soluble drug. It does not dissolve well in the aqueous gastrointestinal fluid, which means it is not absorbed well via the oral route, because a drug can cross cell membranes when it is dissolved in the gastrointestinal fluid.

Authors

  • Abid Mehmood Yousaf
    Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Pakistan.
  • Sundas Zulfiqar
    Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan.
  • Yasser Shahzad
    Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Pakistan.
  • Talib Hussain
    Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Pakistan.
  • Tariq Mahmood
    Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan.
  • Muhammad Jamshaid
    Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan.

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