Optimization of fuzzy c-means (FCM) clustering in cytology image segmentation using the gray wolf algorithm.

Journal: BMC molecular and cell biology
Published Date:

Abstract

BACKGROUND: Image segmentation is considered an important step in image processing. Fuzzy c-means clustering is one of the common methods of image segmentation. However, this method suffers from drawbacks, such as sensitivity to initial values, entrapment in local optima, and the inability to distinguish objects with similar color intensity. This paper proposes the hybrid Fuzzy c-means clustering and Gray wolf optimization for image segmentation to overcome the shortcomings of Fuzzy c-means clustering. The Gray wolf optimization has a high exploration capability in finding the best solution to the problem, which prevents the entrapment of the algorithm in local optima. In this study, breast cytology images were used to validate the methods, and the results of the proposed method were compared to those of c-means clustering.

Authors

  • Maryam Mohammdian-Khoshnoud
    Department of Biostatistics, School of Public Health and Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Ali Reza Soltanian
    Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Arash Dehghan
    Department of Pathology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Maryam Farhadian